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23andMe DNA Test Review: It’s Right For Me But Is It Right for You?

I have been eager to find out my genetic predispositions for some time now. Thus, when 23andMe had an incredible one day sale for their phenotype DNA test, I just could not pass by such an opportunity to get what I wanted for me, while simultaneously doing a review of this new and interesting product for you.

The main question I was trying to answer was: Is it worth doing the phenotype DNA test?

In the end, my conclusion is that it is. However, for reasons listed below, other people may reach a different conclusion for themselves. Hopefully, after reading my review, you would be in a better position to make an informed decision whether such a product is right for you too. In order to accomplish that I will start with a brief video introduction to what is DNA in general and phenotype (or SNP) DNA in particular. Then, I will look at the process of taking the test and show you a video of how I did it myself. Consequently, I will proceed by looking at the associated costs as well as some of the issues surrounding the pro’s and con’s of getting the test done. Finally, I will end with my personal verdict of the product.

One of the really great things about 23andMe is the fact that they provide a sea of useful information for those who are interested in learning more about their genome and the interpretation of specific genes. For starters, you can visit the 23andMe YouTube Channel and watch some short educational videos about genetics. Here are the 3 most relevant and informative clips:

Genetics 101: What is DNA?

 

Genetics 101: What is a SNP (Single Nucleotide Poliymorphism)

 

What is Phenotype?

The Testing Process

During my Singularity 1 on 1 podcast interviews with a number of experts such as Aubrey de Grey, Terry Grossman and Andrew Hessel, I was told repeatedly that tests such as 23andMe’s personal genome service are among several tests that are worth doing. Given that, at best, I have a very limited knowledge of the field, I thought that I’d listen to their advice.

Here is how the process works:

The Saliva Sample DNA Test Kit

 

Lab Processing of Saliva Samples

 

The Costs

Recently, the price for 23andMe’s personalized genome service went down from a one time fee of $199 to the current $99 USD. On top of that you have to pay kit shipping costs to and from your address plus $9 monthly on-line membership fee for one year. Thus, provided that you live somewhere in continental US and pay the full price, you should expect:

$99 + (12months X $9 each) + roughly $30 for shipping = $237 (total cost for the year) 

In my case I took advantage of a one-day DNA Day Sale and thus had to pay only the shipping and the $9 monthly fee for 12 months. Since I am located in Canada my shipping was about $50 and hence my total yearly cost will end up being around $158.

Let me also say that in my opinion the $99 one time fee is a fair amount to pay for what you get so don’t feel that you will be overpaying if you order your kit now. This way you can get your results in the fastest way possible. However, if you are interested in getting the best price possible, then I recommend that you start following the Spittoon – the 23andMe blog. There you can be among the first to hear about any future promotional discounts and sales you can take advantage of.

Full Genome Mapping vs. Phenotype (SNP) DNA Test

Now that we’ve covered the mechanics and the costs, it is time to mention at least some of the more important issues related to DNA testing in general and phenotype or SNP DNA testing in particular.

A big part of arguing for or against any test comes from understanding its goals, its accuracy and its implications. Thus, the first step of deciding, if it is worth doing for you or not, consists in finding out what the test does and does not do.

For starters, make sure you are clear that this is not a complete mapping of your personal genome. What 23andMe offers is a SNP DNA test. This means is that it does not map and examine all your 3 billion genome base pairs but tests only what are arguably the most important 1 million snips of your DNA. While this may be a small part of your total genome it is supposed to be a rather revealing one. In fact, it is for this reason that the test is so affordable. Otherwise, you would be looking to pay upwards of many thousands of dollars rather than the mere couple of hundred you would be paying with 23andMe. In addition to cost, another advantage of the SNP test is that it is much faster while the main disadvantage is that it is less accurate. So, make sure you understand the differences and recognize the pro’s and con’s of each test.

In terms of general accuracy, having a specific gene does not necessarily guarantee a specific or certain type of (health) outcome. Though the exact importance of your genes is still very much a matter of scientific debate, currently the predominant opinion claims that genes determine only about 20-30% of the outcome. The other 70-80% are a result of your environment and life choices such as nutrition, sleep and stress patterns, physical activity etc. Thus no DNA test can or will ever predict your future. At best, what it can do is provide you with a good idea of your odds but how you play those is up to you.

Can you handle the truth?

While the issues mentioned above pertain to the accuracy of DNA testing, the bigger issues are moral ones. So even if we can have perfectly accurate DNA test results, for many, the biggest question, at least at the personal level, is:

“Do I really want to know that?”

For example, when I told my family that I have sent a saliva sample for testing, my sister-in-law said that she does not really want to know what are her chances of developing breast cancer. So if you feel the same way and prefer to not know, then, you definitely should not take the test. I start from the presumption that knowledge is always better than ignorance, even if many may adopt the “ignorance is bliss” attitude.

There is also a whole other spectrum of legal, practical, political and ethical issues related to DNA testing but I will not dwell on those here for this is not the purpose of my review. All I will say is that it may be good to think through all the potential implications of your results before you actually do the test. (Perhaps you can watch a couple of movies such as Gattaca)

The Results

One thing that surprised me pleasantly was the fact that, even though 23andMe says your results take between 6 and 8 weeks, I had mine ready and uploaded to my on-line profile only 2 weeks after sending my sample.

Below is a screen-capture of my health overview home page. Have in mind that this is only a small fraction of a sea of personal information that 23andMe provides you with. In fact, I still haven’t had the chance to read even half of it. 

My 23andMe Profile Health Overview

For reasons of privacy I will not go into all the minute details of my personal results but you should know that your DNA results are grouped into four main areas: Disease Risks, Carrier Status, Traits and Drug Response.

Each of those has its own homepage with dozens, if not hundreds, of specific items within its respective group (e.g. disease risks), which are then given a percentage number representing your specific personal risk, as well as the respective average general population risk.

Furthermore, each of those items is also clickable and thus you can go to its specific home page (e.g. Alzheimer’s Disease), where you can read more about your own data and how that disease works or get some technical reports and scientific citations used to compile the information. All in all, we are talking thousands of pages of relevant in-depth scientific information which is regularly updated with the latest research for the duration that you pay your $9 monthly membership fee.

Another interesting element of your results is the information provided about your ancestry along your maternal and paternal lines. Here is a screen-shot of the map representing my maternal line.

Maternal Haplogroup K1b1

For those interested in your family tree, know that there is an optional free “Relative Finder” service on your profile page where you can look for and get in touch with other people who have also opted into the database and you share genes with. In this way you can actually find distant relatives you never knew existed. Interestingly, while I haven’t had the time to use or examine that part of my profile yet, since I did opt into the service, I was already contacted by someone who is a naturalized American of Bulgarian origin. According to 23andMe that person is probably my fifth cousin.

The Verdict

A big part of your decision is what you expect to find out and how you view the usefulness of any such information.

While curiosity was certainly a part of my motivation for taking the test, I had some very real medical concerns too. I come from a family with a long and lethal history of cancer, diabetes and heart disease. That fact has motivated me to make (mostly) healthy life-choices with respect to nutrition and physical activity. Yet, since genes play an important role, I thought that knowing more accurately my genetic predispositions can provide useful new information and prioritize and focus my efforts on specific things that I should and should not do.

I was relieved to find out that my odds are pretty good because I am showing decreased risk for most major ailments such as Heart Disease, Diabetes, Prostate Cancer, Alzheimer’s and Parkinson’s disease. However, even if it were mostly bad news, it would not have been a reason to despair. In fact, I would have been even more motivated to take action and have as healthy a lifestyle as I possibly can.

In the end of the day I strongly believe that 23andMe provides an excellent product and great value for the money. You can say that, given my results, I didn’t make any big discoveries about my genome for there was nothing that really jumped out at me. Yet I did discover and, with every profile update, will continue to find out many important and interesting things both about my genes and my family tree. (Not to mention that I got connected with a person who may turn out to be a distant cousin of mine.)

Furthermore, even if it seems that I have been lucky genetically speaking, it does not mean that I did not benefit from the test. I would argue that the shorter the genetic straw you draw, the more important it is for you to be aware of it. Knowing about the existence of a potential problem is the only way that you can ever be proactive in avoiding it or, if necessary, be active towards resolving it. Indeed, it is a fact that cancer patients who get well educated about their medical condition have three times better chances of surviving than those who don’t put any effort on their own but blindly follow their doctor’s prescriptions.

While genetics is still a relatively new science in its early stages of development, we are already at the level where we can begin benefiting from it. DNA tests are not only here to stay but also a good example of a cutting edge application with serious potential benefits that you can access right now. So, even though in the future such tests will certainly be better, faster, cheaper and more accurate, at least until you are able to do a full mapping of your personal genome for a similar price, I will argue that this product is worth doing.

In short, based on the reasons above, I regularly recommend 23andMe‘s Personal Genome Service to all my friends and relatives. In fact, my wife Julie will be next to send her saliva test.

 

Video Updates:

23andMe vs. the FDA in less than 4 minutes

 

23AndMe issues statement on FDA smackdown

Dear 23andMe Customers,

I wanted to reach out to you about the FDA letter that was sent to 23andMe last Friday.

It is absolutely critical that our consumers get high quality genetic data that they can trust. We have worked extensively with our lab partner to make sure that the results we return are accurate. We stand behind the data that we return to customers – but we recognize that the FDA needs to be convinced of the quality of our data as well.

23andMe has been working with the FDA to navigate the correct regulatory path for direct-to-consumer genetic tests. This is new territory, not just for 23andMe, but for the FDA as well. The FDA is an important partner for 23andMe and we will be working hard to move forward with them.

I apologize for the limited response to the questions many of you have raised regarding the letter and its implications for the service. We don’t have the answers to all of those questions yet, but as we learn more we will update you.

I am committed to providing each of you with a trusted consumer product rooted in high quality data that adheres to the best scientific standards. All of us at 23andMe believe that genetic information can lead to healthier lives.

Thank you for your loyalty to 23andMe. Please refer to our 23andMe blog for updates on this process.

Anne Wojcicki
Co-founder and CEO, 23andMe

 

This is the CBS This Morning interview with 23andMe’s CEO and co-founder Anne Wojcicki.

Sitting down with hosts Charlie Rose, Norah O’Donnell and Gayle King, Anne spoke about how taking the test changed her own life and her goals for 23andMe.

Testing can offer people “a roadmap” for what they could do to potentially stay healthy. As more people test and with enough data, Anne said there is potential to change health care. Her goal is to for people to be empowered with information about their health so that they can be “healthy at 100.”  The goal of having all that information is to better predict health outcomes for people and personalize medicine.

“A million people walking around with their genomes, I believe, is going to be disruptive to the health care system,” she said.

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  • http://twitter.com/CMStewartWrite CMStewart

    Thanks for a thorough explanation and review of gene testing and of the “23andMe” DNA test process and results. Glad to read your genes are well. :) 

  • http://www.facebook.com/people/Julie-Danaylov/679575645 Julie Danaylov

    Sign me up! I can’t wait to try this out myself…I hope 23andMe has another sale soon!

  • Corin Egglestone

    Hi Socrates

    I’m a PhD student at Loughborough University in the UK. For
    my research I’m conducting a survey of people who have either bought a genetic
    test from a company like 23andme, Navigenics, Decodeme etc. or are thinking of
    buying one.  I was
    wondering if you’d be willing to fill it in.

    There’s more information and a link to it at
    http://www-staff.lboro.ac.uk/~lsctre3/survey.html , it should only take about
    10 minutes and would be really great if you could!  If you have any questions then please email
    me at c.t.r.egglestone3@lboro.ac.uk

    Thanks

    Corin Egglestone

  • http://singularityblog.singularitysymposium.com/ Socrates

    OK Corin,
    I just completed your survey!

  • Mike Cariaso

    You can also download your raw data from 
    https://www.23andme.com/you/download/

    and then use Promethease to learn more about your data
    http://www.snpedia.com/index.php/Promethease

  • Corin Egglestone

    Thanks!

  • Monetsable

    is there a toll free number to ask any questions?

  • https://www.singularityweblog.com/ Socrates

    I don’t think that they have a toll free number but they do have these 2 links:

    Genetics 101: https://www.23andme.com/gen101/
    FAQ’s: https://www.23andme.com/help/

  • Jesngu06

    I have a question. On 23andme it shows you the percent of asian. african and european. Now, as a woman who does not have a male involved in this test too, does it only show my maternal side?

  • https://www.singularityweblog.com/ Socrates

    I believe that it ought to show both you maternal and paternal sides…

  • Marshall Myers

    Is there a lst somewhere that actually lists what the $99 package will get me?

    I want information, but I want to know what kinds of information I will get for my money.

    marshall.myers@eku.edu

  • https://www.singularityweblog.com/ Socrates

    I think that all you need to do is go to https://www.23andme.com/ and read as much as you want. They do give a lot of information there.

  • Rose

    I bought this service for a year and their billing policies are terrible. I was billed twice in one month, and I’m unable to cancel their stupid service until the year is over. Not worth the money or the headache.

  • https://www.singularityweblog.com/ Socrates

    Sorry to hear about your problems of double-billing Rose.

    As far as the other problem you cite is concerned I have to say that during the 23andMe registration process you are warned that you must have at least 1 year worth of monthly payments. So that part should not have been a surprise for you.

  • https://www.singularityweblog.com/ Socrates

    Sorry to hear about their slow customer service HM.
    As far as the other problem you cite is concerned I have to say that during the 23andMe registration process you are warned that you must have at least 1 year worth of monthly payments. So that part should not have been a surprise for you for they do warn you that there is a cancellation fee…

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  • jimatheyjo

    im a little confused, the test price on your site says $299 subscription free yet i keep seeing comments about subscriptions, it also mentions subscriptions in your faq’s, so whats correct? do i pay as subscription as well or not?

  • https://www.singularityweblog.com/ Socrates

    Well, to tell you the truth friend 23andMe have changed their business model several times. So, at the time when I did the review i.e. about 2 years ago, they had a one time fee plus a $10 monthly payment for 1 year. This may have changed now for a one time big fee instead. I am not sure but is best to drink water from the spring, so click hear and find out for yourself:
    https://www.23andme.com/

  • Sten

    From 23andme.com for a woman:
    Because your paternal line is determined by the genetics of the Y-chromosome – there is no way to trace a woman’s paternal haplogroup using her own DNA.
    Is your father at 23andMe? Your Paternal Line is the same as his, and you can let the system know about it so you can see your Paternal Line story here. Here’s what to do:
    Invite your father to share genomes.Create your 23andMe Family Tree.Connect your father to your tree.
    If not, you can get your Paternal Line by getting a 23andMe kit for your father. Order a kit now.

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  • http://www.facebook.com/charlesetta.braggs Charlesetta Braggs

    Their so called “live chat” is a farce. Poor, poor customer service in this area. Their response “will get back to you in 2-3 business days” is an example of poor quality of service to their paying customers

  • https://www.singularityweblog.com/ Socrates

    Those are all great questions Marsha. As it right now, I think only you should have access to your personal results. Then, you can choose who you are going to share those with – be it your partner, your family or your doctor…

  • Lillian Nixon

    I have a question for you? How are you obtaining DNA from ancestral entities? I am Scots/Irish or so I have been told all my life. So, how do you find out that information? The main reason I decided to do this is because I have a cousin who was given up for adoption at birth by my Aunt and I would love to try and find him or her.
    Thank you,
    Lillian Nixon

  • http://www.facebook.com/zaim.de.noisy Zaim De Noisy

    yeah $99 is great but $79.95 for shipping is far too expensive, took it anyway because the total is reasonable but….

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  • wudjasay

    I’m confused: So you’re saying I couldn’t find out my actual paternal line because I’m female unless my father participated? He has passed away, but I want to be able to tell if a distant male was a relative or if what my grandmother said was true, that HER grandmother was sleeping with an Irish sailor who was her true love and that HE is the actual relative and not the Mormon polygamist she was married to. Does this make sense and would I be able to determine this lineage?

  • https://www.singularityweblog.com/ Socrates

    Thanks for your help LIttleMike!

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  • lance savage

    I’m interested in hearing if anyone who has subscribed to 23andme has actually verified the information they received by checking with another DNA profiling service.

  • https://www.singularityweblog.com/ Socrates

    That’s a great question Lance, I know that you can actually download your gene data and then search for alternative interpretation of the same genes…

  • lapsang
  • http://www.facebook.com/gary.james.583671 Gary James

    I’m from Canada and I sent my sample in and they said there was not enough DNA to test. Now I have to pay $60 shipping to get a replacement kit, and of course there is no guarantee this one will work either. I followed all instructions very carefully…

  • http://www.genesand.us/ Rob Hunter

    23andMe also released an API in the last few months, so third parties can now develop services that give additional analysis. I was curious about what disease traits I’d pass on to my kids, so I built http://www.genesand.us , and I do believe that other analysis sites will be cropping up this year.

    If you end up with a chance to check out what I’ve done, I’d love some feedback (I just launched the beta about 3 days ago).

  • Scott75

    Why would my 2nd round of testing have to go through a 2nd round of testing?

  • http://www.facebook.com/zaim.de.noisy Zaim De Noisy

    ooooch that hurts, to add more information I’d say finally I’m very happy becuase they paid back 40 euros for shipment delay and my results are great a s expected

  • Harley

    Were you at all concerned with the company’s privacy policy and how they track your online movements after you’ve registered? This is disturbing to me in that their explanation for such behavior is so that they basically “problem solve” by understanding online activities of all the people who participate. I’m all for the genetic research end of this, but their continuous tracking me online is excessive and unnecessary. Do you agree?

  • https://www.singularityweblog.com/ Socrates

    I am not sure I understand what you are referring to my friend?! How can 23anMe track you across the internet?!

  • Suni Nelson

    Nikola, I’m not 100% sure that genes control our health. If you understand the informational field of the body (& the Universe whose same field was just discovered by Aust. Astronomers & documented in professional journal), we are like computers with a submerged intelligence running beneath the cells, the genes, that gets downloaded with beliefs, emotional truama, thoughts, ‘blocks’ to the Source energy flow (the flow keeps us disease free & kicks in our innate body healing). There are tech devices out there now to visual each person’s body. Thus, it is more likely the ‘informational wave’ blocks causing dis-ease; not a gene. I would be questionning Angolina Jolies choice of double masectomy. We all need to question & question somemore; search for information to make our “individual” decisions.

  • https://www.singularityweblog.com/ Socrates

    I agree in the sense that it is not all genes that determine our health. Personal choices to be active and eat healthy, the environment and even our positive mental attitude have all been proven to play a role…

  • Suni Nelson

    True, however people are still unaware of the submerged intelligence ‘informational wave’ in body & Universe. News is slowly coming out.
    Ques: I’m producing a Women of Wellness TEDx type conf. in Palo Alto, CA Oct.-on Future Medicine. The 4th such event as women have demanded to know more truths about natural & non-invasive, non-toxic healthcare. Already have leading speakers. Would Singularity be a good host for this event? or am I barking up the wrong tree? Thx

  • https://www.singularityweblog.com/ Socrates

    No insult intended but to me it sounds too unscientific and too much into the twilight zone…

  • Suni Nelson

    Not insulted; we’ve been programmed in the scientific, which I also appreciate, it’s just missing a piece. All speakers programs have been clinically researched! We must always keep questioning & learning new info to get to truths. The right communication is always another factor I try to work with so people hear & can comprehend. thx for the practice!

  • https://www.singularityweblog.com/ Socrates

    I agree entirely that we need to keep questioning for that is indeed the only way for us to keep learning ;-)

  • https://www.singularityweblog.com/ Socrates

    Ha, the world is a small place ;-)

  • https://www.singularityweblog.com/ Socrates

    I don’t think it would be. Plus, in my case, I am lucky we come of rather different parts of the world…

  • YoureStillDull

    No Subscription – There are still no subscription fees or commitments when purchasing at this updated price. Customers who purchase at this updated price will still enjoy access to all of 23andMe’s current features. As before, if you have not yet met your subscription commitment from a previous purchase, you will continue to be billed until you complete your 12 month commitment. Once you have met your subscription commitment, you will no longer be charged a subscription fee and can enjoy access to the Personal Genome Service on an ongoing basis.

  • norman lein

    I have done the test. It predicted two major health conditions accurately. It was after I had filled in a health questionnaire in which I had reported these conditions. I am hopeful that the accuracy of their reporting was based to any extent on this retroactive information.

    My family origins are northern European in my father’s side and Mediterranean on my mothers. 23and me has only been able to provide links to DNA relatives that had Northern European origins. I suspect that the data base is still to small and is drawing on subscribers that are based in North America with mostly Northern European origins. The lack of a comprehensive and extensive database may be a shortfall and limit the ability of 23andme to provide accurate health and family tree information. I assume that they have dropped their prices to attract more people who will then expand their database. If so, this is a good thing.

  • Brenda Deschesnes

    She still has a “father gene” on the 23rd pair. This gene, and all the other half of her caryotype is her father’s and his ancestors… I don’ think they only use the X and Y chromosomes… if so, this ancestor line is bullshit… Because this chromosomes comes only from a grandma or a grandpa… (NB: sorry for English mistakes) This is why they must use all the characteristic of the caryotype to localise the ancestors…

  • DD Summers

    Thank you for your in-depth review, it has been very helpful in my decision to purchase. My family has a strong history of cancer, heart disease and diabetes. I myself have had issues with pre-cancerous conditions three times which have resulted in lumpectomies, hysterectomy and numerous biopsies. I.Have not been well this year and have not gone to the doctor with my concerns. This test seems to be a great tool for me to use for many reasons.

    However, I am unable to purchase due to living in the State of Maryland! Why are some states not allowing this test? The decline tag stated “state specific clinical laboratory testing statutes in place”. When it declined, it also instructed “to not try to circumvent the law by ordering to another state”. Can you explain this and maybe help guide me with respect to using a family members address in Virginia?

    Thank you

  • Captain Duh

    if you already knew your family has a “lethal” history of cancer and such, WHY…PAY…150 BUCKS TO TELL YOU THAT YOU HAVE A HISTORY OF CANCER AND SUCH???
    You deserve to be suckered out of that dough, pal. I mean a c-note…plus 9 a month for nothing?!?!?! 9 dollars for crap I won’t use past the first ten minutes. Abso stupid people go for that stunt.
    Also, who hasn’t had a close family member with some form of cancer? Thats like saying “I’m thinking of having someone…” never mind. The stupidity of this trumped my analogous fetish.

    No offense. You’re set in life, now. Go and be healthy, wealthy, and wise. At least not so dumb.

    Captain Duh! AWAAAAYYYYYYYYYYYY…………

  • Woo Hoo

    Doesn’t anybody find it troubling that Anne Wojcicki is a co-founder? She is out to gather everything possible about you in order to profit from it, just like her husband, Google co-founder Sergey Brinn, did with Google. Whatever privacy policy they have will be meaningless after they have your information, just like with Google. They are not out to help you, they are out to trick you into giving them (SELLING to you) your most private and personal information in order to make a profit. Sergey failed to meet Google’s motto of “Don’t be evil.” History will now repeat itself in a much worse way with his wife. No telling who they will sell your information to and how they will use it in the future.

  • Durwin Foster

    This was a great article. Thanks. Looking on their website now, I don’t see any mention of this monthly fee after getting the initial report done. Are you aware if that has changed?

  • https://www.singularityweblog.com/ Socrates

    I think the monthly fee perhaps kicks in after the first year but better check with 23andMe for the latest information…

  • https://www.singularityweblog.com/ Socrates

    Yes indeed, they absolutely do let you export the raw data to keep a back up copy or upload to another service for alternative analysis!

  • Whaley

    The test is a birthday gift to myself. I have thought about it for quite some time. I can’t think of a better gift to my grandchild and family. Information is power. The adventurer into my past begins..I look forward to my journey to the past.

  • NorthStar156

    How precise is the geographic origin information? For example, will it show that your ancestors were from France and Bulgaria, or just that they were from Europe?

  • Transhumanity

    I took the test and found the results interesting because it resolved some curiosity about my origin. I was disappointed that I do not have Neanderthal genes in my blood among other things. Overall. the results were not terribly surprising for me because my relatives have done extensive genealogy research on our line.

  • https://www.singularityweblog.com/ Socrates

    Why be disappointed that you don’t have the Neanderthal gene?! I have 2% or so but, though not surprising to those who know me, I don’t take it as something to be proud of or desire ;-)

  • Transhumanity

    My reason for desiring Neanderthal genes is the diversity. In the fight for survival, it is advantageous to have a wide variety of genes to be able to adapt to change. This is only conjecture, but they may have been ahead of their times, living relatively peacefully. It is my contention that they were killed off by ferocious Homo sapiens who till this very day kill their own by the scores of millions and lust for blood and the taking of life for sport.

  • Gebehard

    I am a 66 yrld. VA patient. Can I take these results to and will they be of any use to my health care providor at the VA?

  • https://www.singularityweblog.com/ Socrates

    I can’t say for sure Gebehard. The best place to ask is the VA…

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  • Edgar R. Cowtan

    I live in Canada. I would like to get as much information from the genetic testing as possible. I can appreciate that the FDA has its concerns, but does it have the right to withhold information from a non USA citizen? Perhaps, I should get the testing done by a non USA company?
    Edgar R. Cowtan

  • David

    Based on the FDA’s warning letter, it seems to me that 23andme is making unjustifiable claims about the accuracy and usefulness of their results in order to lure customers into taking the test. Perhaps 23andme is more concerned with making money off of a large DNA sample.

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  • wanda thacker

    I sent off my DNA sample a couple of weeks ago, and i found out from my daughter, which is also having her DNA checked – that I didn’t get to finish my questionnaire. It just skipped over it, and I couldn’t get back to it. I know there were a lot of questions there were important like, “relative finder,” and that is something that I would have wanted to do. I am doing the test because my granddaughter has autism. and she also has MTHFR. I have two questions. Can I finish my questionnaire? Also, I have 3 children that are going to do the dna testing with 23andme, and I want to know if we can still have our DNA compared? Is there a contact number where I can call and discuss this with someone?

  • John Doe

    Not really, since their child’s DNA would have longer runs of homozygosity (not good), and be susceptible to problems associated with inbreeding.

  • John Doe

    It’s not a gene. It’s an entire chromosome, albeit a smaller one than normal. The Y chromosome is passed down the paternal line. The X chromosome is unreliable now due to both males and females having it and the amount of recombinations it takes part in. To identify Y and mt dna haplogroups, they use predetermined SNPs on the Y chromosome and the MT DNA.

  • Rosemary Grado West

    Does 23andMe test for hemophilia, a hereditary disease passed on by the females?

  • Glenn Barres, Jr.

    I believe you can. Whenever I log in there is always a Survey thing going that is in the Dashboard and it is the same questions.

  • Glenn Barres, Jr.

    That doesn’t mean anything. The FDA is not God nor do they set the results of what people do with this information. It’s just that a lot of people are stupid and don’t think so the FDA has to force people to question things. But just because there is a question, doesn’t mean the answer will be bad.

  • Glenn Barres, Jr.

    Where’s the question?

  • Glenn Barres, Jr.

    I kinda do. We are cross-species individuals. Which sounds cool and would be much cooler if most people aren’t also cross-species. I am 8%

  • tanyavautour

    So since I am a female will I only get results from my mother’s mother side and so on? Does it also give results from my mother’s father? I was hoping for info on my mother’s father.

  • Alex G

    I’m hesitant about this primarily because of privacy concerns. Since several courts have ruled that personal online data is not private since the information is on a company’s servers instead of a person’s own personal server, I’m hesitant to have such personal information online. I wonder if they would be willing to mail results & refrain from adding them to the online system (I’m comfortable looking up information about my results myself).

  • JoMarch

    I was just on 23andme’s website and they no longer do the medical history genetic report, which makes this blog a bit obsolete. To me, that would be the most important. And why would I want a membership? Is my DNA going to chang? No, so it’s just a way for them to make more $.

  • https://www.singularityweblog.com/ Socrates

    Actually DNA does change over time and while those changes are subtle they are very important. Thus it is good to do DNA tests every couple of years if you can and follow how your own DNA evolves over time…

  • steftiggertoo

    Socrates and Nancy, I am K1C1. We must be distant cousins. ;)

  • Ruth

    He did not do the test correctly. I wonder how much off the results will be. He started rubbing his cheeks at 6:21 and finished at 6:39. That’s only 18 seconds.

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